Huntington's disease is an incurable neurodegenerative genetic disorder that affects muscle coordination and some cognitive functions, typically becoming noticeable in middle age. It is the most common genetic cause of abnormal involuntary writhing movements called chorea and is much more common in people of Western European descent. The disease is caused by a dominant mutation on either of the two copies of a gene called Huntingtin, which means any child of an affected parent has a 50% risk of inheriting the disease. Physical symptoms of Huntington's disease can begin at any age from infancy to old age, but usually begin between 35 and 44 years of age. The mutation of the Huntingtin gene codes for a different form of the "huntingtin" protein, whose presence results in gradual damage to specific areas of the brain. The exact way this happens is not fully understood. Genetic counseling has developed to inform and aid individuals considering genetic testing. The earliest symptoms are a general lack of coordination and an unsteady gait. As the disease advances, uncoordinated, jerky body movements become more apparent, along with a decline in mental abilities and behavioral and psychiatric problems. Although the disorder itself is not fatal, complications such as pneumonia, heart disease, and physical injury from falls markedly reduce life expectancy. There is no cure for HD, and full-time care is often required in the later stages of the disease. (more...)
Recently featured: Pauline Fowler – Nikita Khrushchev – Castle
Archive – By email – More featured articles...Did you know...
From Wikipedia's newest articles:
- ... that the position of Dean Ireland's Professor of the Exegesis of Holy Scripture at Oxford was endowed by John Ireland, who was Dean of Westminster for more than 25 years?
- ... that the Patrick Henry Brittan House in Montgomery, Alabama, was built in 1858 by the 10th Secretary of State of Alabama?
- ... that Putsy Caballero is the youngest player ever to play in a game at third base in Major League Baseball history?
- ... that Archiinocellia is the only snakefly fossil genus from British Columbia and one of only two from Canada?
- ... that designated heritage designs by the early 20th-century Canadian architect Neil R. Darrach can be found in both St. Thomas, Ontario, and Regina, Saskatchewan?
- ... that Memories Off 5: Encore's PlayStation Portable port includes a built-in screen capture feature to download images onto a memory stick?
- ... that former professional footballer Tony Larkin helped to establish Britain's first football academy for visually impaired players?
- ... that a class action lawsuit was brought against a Pennsylvania school district for allegedly using webcams in school-issued laptop computers to spy on students at home? Archive – Start a new article –
In the news |
|---|
|
On this day... |
|
February 27: Purim begins at sunset (Judaism, 2010); Independence Day in the Dominican Republic (1844)
More anniversaries: February 26 – February 27 – February 28 Archive – By email – List of historical anniversaries It is now February 27, 2010 (UTC) – |
|
Other areas of Wikipedia
- Help desk – Ask questions about using Wikipedia.
- Reference desk – Serving as virtual librarians, Wikipedia volunteers tackle your questions on a wide range of subjects.
- Village pump – For discussions about Wikipedia itself, including areas for technical issues and policies.
- Community portal – Bulletin board, projects, resources and activities covering a wide range of Wikipedia areas.
- Site news – Announcements, updates, articles and press releases on Wikipedia and the Wikimedia Foundation.
- Local embassy – For Wikipedia-related communication in languages other than English.
Wikipedia's sister projects
Wikipedia is hosted by the Wikimedia Foundation, a non-profit organization that also hosts a range of other projects:
| Commons Free media repository | Wikinews Free-content news | Wiktionary Dictionary and thesaurus | |||
| Wikiquote Collection of quotations | Wikibooks Free textbooks and manuals | Wikisource Free-content library | |||
| Wikispecies Directory of species | Wikiversity Free learning materials and activities | Meta-Wiki Wikimedia project coordination |
Wikipedia languages
This Wikipedia is written in English. Started in 2001, it currently contains 3,207,453 articles. Many other Wikipedias are available; some of the largest are listed below.
- More than 500,000 articles: Deutsch · Español · Français · Italiano · Nederlands · 日本語 · Polski · Português · Русский
- More than 150,000 articles: Català · Čeština · Magyar · Norsk (bokmål) · Suomi · Svenska · Українська · 中文
- More than 100,000 articles: العربية · Bahasa Indonesia · Dansk · Esperanto · עברית · 한국어 · Lietuvių · Română · Slovenčina · Српски / Srpski · Tiếng Việt · Türkçe
- More than 40,000 articles: Bahasa Melayu · Български · Eesti · Ελληνικά · English (simple) · Euskara · فارسی · Galego · Hrvatski · Norsk (nynorsk) · Slovenščina · ไทย
|
Internet Search Engine Database
The algorithm (or algo) is basically the ranking formula that each search engine uses to determine the relevancy of any page that the crawler finds. ...
To 301 or Not to 301, That Is the Question ADOTAS
25 Tips For Better Search Engine Positioning ozCarGuide
Best SEO Company India BigNews.biz (press release)
all 52 news articles »
[MyIS]Zips
hu, 18 Feb 2010 06:34:30 GM
Since I know everyone hates it when I post site update news about CS-Nation, the very site that you're reading, I figured I'd give you a two for one special today. Yes, we have updated our . main. index a little bit.
Q. my yahoo is my default main page. i do delete cookies on sign out. but, when i sign in it just goes right back to the my yahoo sign in main page. anyone know the trick?
Asked by twd - Wed Nov 4 11:47:55 2009 - - 1 Answers - 0 Comments
A. you will be deleting the keep me signed in for 2 week option by deleteing your browser cookies, have a nice day
Answered by HaSiCiT Bust A Tie A1 TieBusters - Wed Nov 4 19:44:37 2009


![[Site Update] Main Page Update & Bad Company 2 Beta Key Giveaway](/ZBPr7-XEBJGRATAVZNTYNGBGr7-ABVGNAFPs707-s707-n807-CGGUq8-YEHs8-KCFNr7-RTNZVs7-TEBr7-FGBUFOZHUGr7-ARCB-out.jpg)